| Exposition au BPA via les bouteilles en polycarbonate |
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Cette étude a suivi 77 étudiants de Harvard. Les dosages urinaires étaient faits après une semaine sans utilisation de bouteilles en polycarbonate puis après une semaine de consommation : l'augmentation était de 69 %. Ce résultat confirme que la source de l'imprégnation en BPA vient de l'ingestion et qu'il serait donc facile de réduire l'imprégnation au BPA Use of Polycarbonate Bottles and Urinary Bisphenol A Concentrations Jenny L. Carwile et al doi: 10.1289/ehp.0900604 (available at http://dx.doi.org/) Online 12 May 2009 ehponline.org http://www.ehponline.org/docs/2009/0900604/abstract.pdf ABSTRACT Background Bisphenol A (BPA) is a high production-volume chemical commonly used in the manufacture of polycarbonate plastic. Low-level concentrations of BPA in animals and possibly in humans may cause endocrine disruption. Whether ingestion of food or beverages from polycarbonate containers increases BPA concentrations in humans has not been studied. Objectives To examine the association between use of polycarbonate beverage containers and urinary BPA concentrations in humans. Methods We conducted a non-randomized intervention of 77 Harvard College students to compare urinary BPA concentrations collected following a washout phase of one week to those taken after an intervention week during which most cold beverages were consumed from polycarbonate drinking bottles. Paired t-tests were used to assess the difference in urinary BPA concentrations before and after polycarbonate bottle use. Results The geometric mean urinary BPA concentration at the end of the washout phase was 1.2 μg/g creatinine, increasing to 2.0 μg/g creatinine following one week of polycarbonate bottle use. Urinary BPA concentrations increased by 69% following polycarbonate bottle use (p<.0001). The association was stronger among participants who reported ≥90% compliance (77% increase; p<.0001) than among those reporting <90% compliance (55% increase; p=0.03) but this difference was not statistically significant (p=0.54). Conclusions One week of polycarbonate bottle use increased urinary BPA concentrations by two thirds. Regular consumption of cold beverages from polycarbonate bottles is associated with a substantial increase in urinary BPA concentrations irrespective of exposure to BPA from other sources.
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| Mise à jour le Vendredi, 15 Mai 2009 13:35 |
